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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP3
All Species:
9.09
Human Site:
S252
Identified Species:
22.22
UniProt:
Q7Z494
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z494
NP_694972.3
1330
150864
S252
S
M
I
Q
L
Q
Q
S
F
R
G
P
E
F
A
Chimpanzee
Pan troglodytes
XP_516758
2073
234018
S265
S
M
I
Q
L
Q
Q
S
F
R
G
P
E
F
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863943
2040
230770
G235
Q
L
Q
Q
S
F
R
G
P
E
F
A
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNH6
1324
150168
P248
S
M
I
Q
L
P
Q
P
F
R
G
P
E
F
A
Rat
Rattus norvegicus
XP_343462
1325
150597
P248
S
M
I
Q
L
Q
Q
P
F
R
G
P
E
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514031
1275
145541
C243
L
W
S
N
T
V
R
C
Y
L
I
W
T
D
E
Chicken
Gallus gallus
XP_418790
1315
149161
S237
S
M
M
Q
L
Q
Q
S
F
R
G
P
E
F
A
Frog
Xenopus laevis
Q6AZT7
1300
148301
F235
Q
S
F
R
G
P
E
F
A
H
S
S
I
D
V
Zebra Danio
Brachydanio rerio
XP_691073
1303
148244
F235
Q
T
H
R
G
P
E
F
A
H
S
L
I
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203493
1012
113472
D12
S
S
F
P
N
D
G
D
D
D
D
Q
P
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
N.A.
61.5
N.A.
88.8
87.9
N.A.
78
83.9
76.9
69.9
N.A.
N.A.
N.A.
N.A.
30.9
Protein Similarity:
100
62.4
N.A.
63
N.A.
93.3
93.3
N.A.
86.2
90.7
86.5
82.9
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
93.3
N.A.
0
93.3
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
86.6
93.3
N.A.
13.3
100
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
20
0
0
10
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
10
10
10
0
0
30
0
% D
% Glu:
0
0
0
0
0
0
20
0
0
10
0
0
50
0
10
% E
% Phe:
0
0
20
0
0
10
0
20
50
0
10
0
0
50
0
% F
% Gly:
0
0
0
0
20
0
10
10
0
0
50
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
20
0
0
10
0
0
% H
% Ile:
0
0
40
0
0
0
0
0
0
0
10
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
50
0
0
0
0
10
0
10
0
0
0
% L
% Met:
0
50
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
30
0
20
10
0
0
50
10
0
0
% P
% Gln:
30
0
10
60
0
40
50
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
20
0
0
20
0
0
50
0
0
0
0
0
% R
% Ser:
60
20
10
0
10
0
0
30
0
0
20
10
0
10
10
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
30
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _